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Thursday 28, Jan 2010

  Protein behind Chronic Rhinosinusitis with Polyps tracked down

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chronic-rhinosinusitisAccording to a study by researchers from Johns Hopkins, a protein that was known to stimulate growth of blood vessel has now been found to be behind the cell overgrowth in the development of polyps characterizing one of the most severe forms of sinusitis.

Jean Kim, M.D., Ph.D., assistant professor in the Departments of Otolaryngology and Allergy and Clinical Immunology at the Johns Hopkins University School of Medicine, and a researcher at the Johns Hopkins Allergy and Asthma Center at the Johns Hopkins Bayview Medical Center, said that the sinusitis is not subtle in its nature.

This finding has given a new target to scientists to develop novel therapies for treating this disease form, which usually resist all present-day treatments.

Wednesday 16, Dec 2009

  Protein responsible for chronic rhinosinusitis with polyps tracked down

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Protein responsible for chronic rhinosinusitis with polyps tracked downResearchers from the Johns Hopkins have suggested during a study that a protein, vascular endothelial growth factor, or VEGF, a protein important for normal blood vessel growth, is responsible for overgrowth of cells in development of polyps characterizing one of the most severe forms of sinusitis.

This finding by Johns Hopkins researchers is expected to give a new target for development of new therapies for treating this disease form, which usually resist all present forms of treatment.

The findings were published in the Dec. 1 American Journal of Respiratory and Critical Care Medicine and suggested that doctors can treat sinusitis in patients with polyps by making use of therapies that minimize VEGF in sinus tissues.

Tuesday 01, Dec 2009

  Novel therapy development for chronic sinusitis may be promoted by a new target

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Novel therapy development for chronic sinusitis may be promoted by a new targetAccording to researchers at the Johns Hopkins, a protein that is known to stimulate growth of blood vessel is responsible for the cell overgrowth in polyps’ development signifying one of the most severe forms of sinusitis.

It is considered by many scientists that this result finding will be more than helpful when it comes to developing novel therapies to treat this disease form that typically resists all current treatments.

The findings suggest that medical practitioners could treat sinusitis in patients with polyps by making use of therapies that minimize VEGF (vascular endothelial growth factor) in sinus tissues.

 

 


Sunday 20, Sep 2009

  Steroid Nasal spray and antibiotic therapy effective for acute sinusitis

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Steroid Nasal spray and antibiotic therapy effective for acute sinusitisAccording to a recently published review, more than 37 million Americans suffer from nasal congestion, sinus pressure, cough and postnasal drip that accompany sinusitis.

Though doctors prescribe antibiotics for relieving acute sinusitis but that may develop following a chest cold, a combination of steroid nasal spray and antibiotic therapy is the best option when it comes to easing symptoms and speedy recovery, as per researchers from Israel.

Sinusitis is an inflammation of the mucous membranes that is lined between the sinus cavities. Doctors usually prescribe steroid sprays like Nasonex, Flonase, and Rhinocort for treating chronic sinusitis and allergies symptoms.

It was remarked that 73 percent of patients treated with nasal steroids gained relief or significant improvement of symptoms compared with only 66.4 percent of patients receiving placebo during the study period.

Tuesday 12, May 2009

  Steroids for sinusitis!

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Steroids for sinusitis!If we look for figures we’ll see that almost 37 million Americans suffer from acute sinus pressure, nasal congestion and similar allergies every year. The most common therapy recommended by the doctors include antibiotics which do prove to be a big relief from this acute condition but this is followed by a chest cold most of the times.

However, the good news is that a new research carried on by Isareli experts says that steroid nasal sprays can help ease symptoms of sinus in a much better way and also aid in speedy recovery. This can prove to be highly beneficial for patients suffering from the same because sinus is an extremely painful condition.

The research was carried forth by carrying out randomized trials on nearly 2000 participants suffering from severe sinusitis. The participants who had to undergo X-ray or nasal endoscopy to confirm the diagnosis either received a placebo or intranasal corticosteroids for atleast two or three weeks. They were administered with this either only with steroids or in combination with antibiotics. The Intranasal corticosteroids employed primarily included fluticasone propionate (Flonase), mometasone furoate (Nasonex) and budesonide (Rhinocort).

Monday 11, May 2009

  Steroid therapy for acute sinusitis!

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Steroid therapy for acute sinusitis!The statistics show that every year, almost 37 million Americans suffer from the sinus allergies which include nasal congestion, postnasal drip leading to severe sinusitis.

For those of you unknown to this condition must know that sinusitis is basically the inflammation of the mucous membrane that line the sinus cavities. There are a number of steroid sprays available like Flonase, Nasonex and Rhinocort which have been proved to be highly beneficial for the reduction of this inflammation. This also leads to promoting the drainage in the sinuses which are often prescribed to treat chronic sinusitis and other similar allergies symptoms.

A few reviews have appeared in the issue of The Cochrane Library , a publication of The Cochrane Collaboration which is an international body that evaluates research in all possible areas of health care. These systematic reviews have drawn some great evidence-based conclusions about medical practice after considering the content and quality of existing trials on the subject.

However, there are few aftermaths of employing nasal steroids for conditions like sinusitis and the like but one should know that they are fairly expensive. The National Institute of Allergy and Infectious Diseases, has released a paper which says that diagnosing and treating sinusitis costs Americans nearly $6 billion per year.

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