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Thursday 18, Mar 2010

  Relief comes easy for Pneumonia patients with steroids

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Relief comes easy for Pneumonia patients with steroidsAccording to a study by researchers from the UT Southwestern Medical Center, steroids can easily facilitate the recovery process for patients affected by pneumonia and even better than use of antibiotics alone.

It was suggested by the study that health of an affected patients can be restored back when steroids and antibiotics are combined.

Dr. Robert Hardy, Study’s Senior Author & Associate Professor of Internal Medicine and Pediatrics, said that clinic trial would soon be performed for confirm the finding. It is worth noting that a combination of steroids and antibiotics can provide relief to a patient in the midst of an asthma attack (M pneumoniae infection).

Monday 15, Feb 2010

  Children may find it difficult to handle chicken pox and steroids

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Children may find it difficult to handle chicken pox and steroidsChildren who suffer from chicken pox and administered with steroids run an increased risk of a more severe case of the virus leading to death.

This finding was disclosed by pediatric oncologists at the Brenner Children’s Hospital, part of Wake Forest University Baptist Medical Center.

Chicken Pox, though mild in its nature, may turn fatal in acute cases. Prior to the discovery of varicella vaccine, around 12,000 people used to die from chicken pox on a yearly basis.

Wednesday 10, Feb 2010

  Phase III GvHD trial preliminary results announced

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phase-iii-gvhd-trial-preliminary-results-announcedOsiris Therapeutics, Inc. has announced the preliminary results for two phase III trials evaluating Prochymal for the treatment of acute graft versus host disease (GvHD).

Graft-versus-host disease is considered to be one of the most dreadful health complications of bone marrow transplantation. It is a fatal complication with no approved treatment option till date.

It was remarked by C. Randal Mills, Ph.D., President and Chief Executive Officer of Osiris Therapeutics that more analysis is suggested for gaining appreciation of the rigorous, double-blind, placebo-controlled trial results.

Friday 15, Jan 2010

  Pneumonia patients can expect relief with steroids

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Pneumonia patients can expect relief with steroidsPatients suffering from pneumonia can expect significant relief in a short span of time for long term with steroids, as per a study by researchers from the UT Southwestern Medical Center.

It was suggested by the study that health of a pneumonia patient can be restored when steroids are used in a combination with antibiotics as compared to the use of antibiotics alone.

It was also noted that while steroids are effective for treating lung inflammation, antibiotics are effective for killing the bug.

Dr. Robert Hardy, Study’s Senior Author & Associate Professor of Internal Medicine and Pediatrics, led the study and noted that studies in future would happen for confirming these findings.

Friday 15, Jan 2010

  Black teens more resistant to steroids

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Black teens more resistant to steroidsBlack teens suffering from asthma are more resistant to steroid treatment than their white counterparts, as per a research conducted at the National Jewish Medical and Research Center. It was suggested by the study that inhaled steroids may prove to be one of the best ways for asthma control management in an effective manner.

Joseph Spahn, M.D., a pediatric allergist and director of the Immunopharmacology Lab at National Jewish, remarked that African-American children are more prone to be resistant to asthma steroid therapy than white children.

This study was published in the Journal of Allergy and Clinical Immunology.

It is believed that future studies are in the pipeline for determining if the black teens also have a more vigorous immune response to airway inflammation.

Sunday 27, Dec 2009

  Regular asthma dosages must for continued benefits

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Regular asthma dosages must for continued benefitsChildren suffering from asthma and being administered with steroids in the younger age but discontinuing the same after some time may not benefit from the same results, as per results from a comprehensive childhood asthma study.

This study finding came from the Childhood Asthma Management Program (CAMP) clinical trial that involved treatment of more than 1,000 children with mild-to-moderate asthma. Children were divided into three groups. While one received twice-daily budesonide and an inhaled corticosteroid, the second group received nedocromil (an inhaled non-steroid medication), and the third received placebo. All these groups also received albuterol, a bronchodilator, and oral corticosteroids for treating asthma symptoms.

The findings of this study are expected to offer new insights to members of the medical fraternity when it comes to formulation of new asthma treatment plans.

Sunday 13, Dec 2009

  Steroid treatment may be resisted by black asthmatic children

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Steroid treatment may be resisted by black asthmatic children Joseph Spahn, M.D., a pediatric allergist and director of the Immunopharmacology Lab at National Jewish, has remarked that black asthmatic teens are more resistant to steroid treatment for curing asthma than the white teens. The study was published in the Journal of Allergy and Clinical Immunology.

It is important to note here that many recent epidemiological studies have suggested that the black teens run a higher risk of being sick and suffer from a greater mortality rate than the white teens.

It was remarked by the involved researchers that further studies are required to ascertain if the black teens also run a higher risk of a more vigorous immune response to airway inflammation or not.

Friday 04, Dec 2009

  Preliminary results of Phase III GvHD trials announced

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Preliminary results of Phase III GvHD trials announcedPreliminary results for two phase III trials evaluating Prochymal for the treatment of acute graft versus host disease (GvHD) have been announced by Osiris Therapeutics, Inc.

GvHD is considered to be one of the most common complications of bone marrow transplantation that is a life-endangering ailment without any approved treatment option till date.

C. Randal Mills, Ph.D., President and Chief Executive Officer of Osiris Therapeutics, remarked that further analysis is required to gain a complete appreciation of the rigorous, double-blind, placebo-controlled trial results.

 


Thursday 03, Dec 2009

  Difference in level of asthma steroid treatment response

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Difference in level of asthma steroid treatment responseAs per the results of a research conducted at the National Jewish Medical and Research Center, the bodies of black asthmatic children are more likely to turn down the benefits of steroid treatment as per Joseph Spahn, M.D., a pediatric allergist and director of the Immunopharmacology Lab at National Jewish.

It was highlighted that black children are more resistant to asthma steroid therapy than their white counterparts.

The results of this study were published in the Journal of Allergy and Clinical Immunology. It is expected that more studies would soon be in the pipeline to ascertain if the black teens are also prone to have a more vigorous immune response to airway inflammation or not.

Sunday 15, Nov 2009

  Young patients with knee disorder can get active with cellular grafting

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Young patients with knee disorder can get active with cellular graftingAdam Vasser of Los Altos, California, was an active kid with a flair for baseball until one day when his heart was attacked by a mysterious virus requiring a need for a heart transplant. He underwent steroid treatment in the long term for preventing rejection of transplant leaving him to lead his life with osteonecrosis, an excruciating knee disorder.

Now at 23 and undergoing 15 knee and heart surgeries, he is back to play baseball again, all due to a new technique known as cellular grafting.

The 60-minute surgery, known as osteoprogenitor cellular grafting, involved scooping out the dead bone and thereafter filing the space in with a new cellular matter. It was theorized by Goodman that use of bone cells is better than using traditional bone grafting for these kinds of cases. A longer-term follow-up study with a larger number of patients was recommended by Goodman, an orthopedic surgeon Stuart Goodman, MD, PhD.

 


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