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Monday 25, Apr 2011

  Children Who Take Steroid Drugs For Nephrotic Syndrome Are Protected From Bone Loss

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Children Who Take Steroid Drugs For Nephrotic Syndrome Are Protected From Bone Loss According to a new study, children who use steroid drugs for nephrotic syndrome do not suffer from osteoporosis, which is a common side effect of steroid treatment methods in adults.

Childhood nephrotic syndrome, which is thought to affect 3 out of 100,000 children, is one of the most common chronic kidney diseases in children. Although it does not impair kidney function, it weakens ability of the body to remove salt and water in the blood causes swelling of the legs and stomach and around the eyes.

Dr. Leonard said that the findings of this report may be used to assure parents and doctors about steroid treatments too help children with nephrotic syndrome that steroids do not increase their risk of osteoporosis.

Thursday 10, Feb 2011

  Infliximab better than steroids for Crohn’s Therapy

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Infliximab better than steroids for Crohn's TherapyIn a study with 129 patients, initial treatment with infliximab plus azathioprine in patients with moderate to severe Crohn’s disease leads to more remissions when compared to a standard approach starting with topical or systemic steroid treatment.

Geert D’Haens, M.D., said at the 13th United European Gastroenterology Week, “Steroids are not necessary for treating Crohn’s disease.”

The study was sponsored by Centocor and Schering-Plough.

Wednesday 05, Jan 2011

  Steroids help kidney patients preserve kidney function

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Steroids help kidney patients preserve kidney functionAccording to a study appearing in an issue of the Journal of the American Society of Nephrology (JASN), patients with IgA nephropathy can benefit from use of steroids. It was revealed by the study that individuals suffering from the kidney disease can prevent or delay loss of kidney function with steroids.

The list of study co-authors included Simeone Andrulli, Lucia Del Vecchio, Francesco Locatelli (Ospedale di Lecco), Antonello Pani (Ospedale di Cagliari), Patrizia Scaini (Ospedale di Brescia), Giambattista Fogazzi (Ospedale Maggiore di Milano), Bruno Vogt (Inselspital di Berna), Vincenzo De Cristofaro (Ospedale di Sondrio), Landino Allegri (Ospedale di Parma), Lino Cirami (Ospedale di Firenze), and Aldo Deni Procaccini (Ospedale di Foggia).

The kidney complication is an autoimmune disease, which is regarded as a major cause of end-stage failure of the kidneys in younger people.

Thursday 30, Dec 2010

  Steroids beneficial for preserving kidney function

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Steroids beneficial for preserving kidney functionAccording to a finding published as part of a study in an issue of the Journal of the American Society of Nephrology (JASN), treatment with steroids can prove to be a beneficial option for delaying or preventing loss of kidney function in patients with IgA nephropathy, a type of kidney disease.

The kidney complication is an autoimmune disease affecting the kidneys and is considered as a major cause of end-stage failure of the kidneys in younger people.

The list of study co-authors included Simeone Andrulli, Lucia Del Vecchio, Francesco Locatelli (Ospedale di Lecco), Antonello Pani (Ospedale di Cagliari), Patrizia Scaini (Ospedale di Brescia), Giambattista Fogazzi (Ospedale Maggiore di Milano), Bruno Vogt (Inselspital di Berna), Vincenzo De Cristofaro (Ospedale di Sondrio), Landino Allegri (Ospedale di Parma), Lino Cirami (Ospedale di Firenze), and Aldo Deni Procaccini (Ospedale di Foggia).

Wednesday 01, Sep 2010

  Kidney function preserved with steroids

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Kidney function preserved with steroidsTreatment with steroids could lead to prevention or delay loss of kidney function in patients with IgA nephropathy, a type of kidney disease. This finding will be disclosed by a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

This kidney complication is an autoimmune disease that affects the kidneys and regarded as a major cause of end-stage failure of the kidneys in younger people.

The list of study co-authors included Simeone Andrulli, Lucia Del Vecchio, Francesco Locatelli (Ospedale di Lecco), Antonello Pani (Ospedale di Cagliari), Patrizia Scaini (Ospedale di Brescia), Giambattista Fogazzi (Ospedale Maggiore di Milano), Bruno Vogt (Inselspital di Berna), Vincenzo De Cristofaro (Ospedale di Sondrio), Landino Allegri (Ospedale di Parma), Lino Cirami (Ospedale di Firenze), and Aldo Deni Procaccini (Ospedale di Foggia).

Tuesday 27, Jul 2010

  Chicken pox and steroids may be difficult to handle for children

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Chicken pox and steroids may be difficult to handle for childrenPediatric oncologists at the Brenner Children’s Hospital, a part of the Wake Forest University BaptistMedical Center , have disclosed that young children suffering from chicken pox and treated with steroids could be at a risk for a more severe virus incidence that may lead to death.

This finding is expected to act as a warning bell for medical practitioners who have been treating their young patients afflicted with chicken pox with steroids.

Chicken Pox, though mild in its nature, could be devastating in some cases. It is worthwhile to note here that as many as 12,000 people used to die because of this disease every year before the varicella vaccine was discovered.

Wednesday 26, May 2010

  Potential cancer drug can help asthma patients

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Potential cancer drug can help asthma patientsR-roscovitine, a drug that is presently being tested for cancer, may prove for treating asthma as well, according to a research.

The drug can prove effective for killing certain immune cells capable of exacerbating symptoms associated with asthma, as per scientists at the University of Edinburgh.

The finding is expected to offer an alternative way for treating asthma in patients who show resistance to steroids that are commonly used and prescribed in asthma treatments.

Thursday 22, Apr 2010

  Severe kidney disease can be caused by mutant gene

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Severe kidney disease can be caused by mutant geneRecessive mutations in a gene called phospholipase C epsilon or PLCE1 can lead to a severe, early-onset form of kidney disease and renal failure in children, a previously unknown cause. This finding was revealed by scientists at the University of Michigan Medical School.

The mutant gene identification is important for the scientists since PLCE1 affects the development of podocytes, which are specialized cells playing a vital role in the kidney’s ability to remove waste products from blood and retaining important blood proteins.

Friedhelm Hildebrandt, M.D., the U-M’s Frederick G L Huetwell Professor for the Cure and Prevention of Birth Defects, said this is the first report of infants with two mutations in a recessive gene for nephrotic syndrome (resistant to steroid treatment) that nevertheless responded to treatment with steroids.

Saturday 03, Apr 2010

  Risks of stridor and reintubation can be reduced with early steroid use

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Risks of stridor and reintubation can be reduced with early steroid useThe risks of reintubation and stridor can be reduced to a significant extent in high-risk patients with administration of steroids at least four hours before extubation, as per a report.

Dr. Samir Jaber from University of Montpellier I in France and colleagues conducted a quantitative meta-analysis of seven studies and find out the efficacy of prophylactic steroid therapy to prevent reintubation and post-extubation stridor.

It was suggested by the study that steroid treatment is beneficial for reducing the risk of reintubation in trials that enrolled high-risk patients.

Wednesday 24, Feb 2010

  Children with Kawasaki’s disease get relief with steroids

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Children with Kawasaki's disease get relief with steroidsSteroids, when added to the standard form of treatment, are effective in considerably reducing the odds of developing heart damage in children with Kawasaki‘s disease.

This finding was disclosed by a study in an issue of Pediatrics and highlights a gap in knowledge. The study emphasized on benefits of steroid treatment for Kawasaki’s disease and is expected to provide insights to members of the medical fraternity in treating this health concern in an effective manner.

Kawasaki‘s disease is one of the leading causes of acquired heart disease in children with an unknown cause. The symptoms of this complication are red eyes, palms and foot soles, and swollen lymph nodes.

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