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Friday 07, Nov 2014

  Improved Abilities Discovered For Detecting HCG Doping In Sport

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Improved Abilities Discovered For Detecting HCG Doping In Sport

A new peer-reviewed research conducted by Getachew A. Woldemariam and Dr. Anthony W. Butch may place a vital role in the day to come for detecting athletes who are taking human chorionic gonadotropin (hCG) to enhance athletic performance.

Woldemariam and Butch through their research developed ways to specifically measure several forms of hCG in urine. In females, urinary human chorionic gonadotropin is a marker of pregnancy. The new test, by specifically measuring the various forms of hCG in male urine, can better detect athletes who are taking hCG.

Butch remarked this immunoextraction and tandem mass spectrometry method for measuring the major isoforms of chorionic gonadotropin in urine is a significant improvement over currently available immunoassays. Dr. Butch further added that the method has superior analytical specificity and will greatly enhance the ability to detect male athletes who dope with various forms of chorionic gonadotropin.

Dr. Larry Bowers, PCC Scientific Advisory Board Chair and USADA Chief Science Officer, commented that the measurement of male urinary hCG in anti-doping has been an area of concern for many years. Dr. Bowers added this important research has not only developed a sensitive and specific LC-MS/MS assay which will help us to detect the various forms of hCG and those who use it to cheat their competitors, but Woldemariam and Butch have greatly added to our knowledge about hCG excretion after administration. It was further remarked by Bowers that with the specificity of the LC-MS/MS method, it should be possible to provide additional information about the concentration of intact hCG in male urine samples who have not doped and therefore increase the sensitivity of the test.

The World Anti-Doping Agency (WADA), based on the study results, is in the process of developing new guidelines for WADA-accredited labs for conducting tests.

Human chorionic gonadotropin has the ability to stimulate production of Testosterone in the body and is presently classified as a banned substance on the World Anti-Doping Agency list. It is commonly used by athletes and bodybuilders with synthetic anabolic steroids. Medical practitioners recommend this hormone to young boys when their testicles have not dropped down into the scrotum (due to a pituitary gland disorder) in a normal way. Use of HCG is commonly made by athletes and bodybuilders during a steroid cycle to maintain testosterone production and testicle size. Bioavailability of the HCG injection is better with intravenous administration than with subcutaneous administration.

In the last few years, HCG has been marketed for weight loss and it is believed that it can improve mood, assist in fat burning, and reduce hunger. Many elite bodybuilders have successfully used HCG to get rid of stubborn fat and fat accumulated in the abdomen and the thighs without compromising on muscle mass. HCG abuse can result in health complications such as breast enlargement in women, sudden development of facial or pubic hair in adolescents, indigestion, difficulty in breathing, rapid weight or height gain, bloating, and nausea.

The research, which was published in the August issue of Clinical Chemistry, was funded by the Partnership for Clean Competition (PCC).

pdf_iconDownload in PDF: Improved Abilities Discovered For Detecting hCG Doping In Sport

Monday 23, Apr 2012

  Bodybuilding.com founder pleads guilty

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Ryan DeLuca put $20,000 down in 1999 for purchasing a web domain called Bodybuilding.com that went on to become a popular website.

“It’s so cool to be able to start something like this,” DeLuca said when he was just 23 in 2001.

“Mr. DeLuca is strictly liable for misdemeanor violations of the FDA law,” his attorney John Lundquist said. “He wants to put this matter behind himself and continue to move the company forward.”

Monday 27, Feb 2012

  Axis Labs fined and sentenced to probation

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In connection with a mail fraud case, Axis Laboratories LLC was sentenced to one-year probation, penalized $50,000, and asked to surrender $107,000.

The company was charged by government prosecutors of disseminating anabolic steroids disguised as a weight-loss dietary supplement.

DCD LLC and R&D Holdings were also fined for selling adulterated supplements that contained anabolic steroids.

Tuesday 14, Feb 2012

  Fines and probation for Axis Labs

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Axis Labs LLC was sentenced to one-year probation, fined $50,000, and ordered to forfeit $107,000 in connection with a mail fraud case.

Federal prosecutors accused the company of distributing anabolic steroids masquerading as a weight-loss supplement.

DCD LLC and R&D Holdings were also fined for selling adulterated supplements that contained anabolic steroids.

Friday 21, Oct 2011

  Axis Labs accused of mail-order steroid sales

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Axis Labs LLC of Centennial has been charged by the federal authorities with a criminal count of mail fraud on allegations it illegally sold mail-order supplements containing anabolic steroids.

Prosecutors in the U.S. Attorney’s Office for Colorado charged Axis Lab recently in U.S. District Court in Denver.

“It is critically important that consumers know the contents of what they are consuming,” said John Walsh, U.S. Attorney for Colorado, in a press release. “In this case, the product contained synthetic anabolic steroids, and because of its potential for harm, it was a prescription drug that could only be dispensed pursuant to a valid prescription.”

Thursday 20, Oct 2011

  Recall of the dietary supplement

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The Food and Drug Administration notified Superior Metabolic Technologies that Uprizing 2.0 contained a synthetic steroid called superdrol, which is banned by the FDA, as per a press release.

The dietary supplement was sold through retail health food stores in Georgia, Alabama, Arizona, California, Mississippi, New Jersey, South Carolina, and Texas.

The FDA notification led to recall of the dietary supplement.