According to a research published ahead of print in the British Journal of Sports Medicine, presently followed steroid (testosterone) doping tests should be scrapped for international sporting events as they ignore important ethnic variations in hormone activity.

Testosterone and other hormones such as growth hormone that are capable of enhancing testosterone levels are among the most widely abused performance enhancing drugs in sports as per the WADA.

From News-medical.net:

Evidence of abuse is determined by the testosterone: epitestosterone ratio, or T:E ratio for short, in the urine. The threshold is set at above four for everyone, and confirmed by chemical analysis (gas chromatography).

To highlight the inadequacy of the current test, the researchers tested the steroid profiles of football players of different ethnicities, after they had deliberately added steroid to their urine samples.

They used gas chromatography, and took account of a variation (polymorphism) in the UGT2B17 gene.

Previous research has indicated that variations in this gene account for some of the differences in the urinary T:E ratio between men of white and Asian ethnic backgrounds. The gene affects metabolism, and therefore the rate at which testosterone is passed out of the body into the urine.

It was suggested that a single indiscriminate threshold for picking up steroid abuse in international sport is no fit for the purpose.

Tags: growth hormone, performance enhancing drugs in sports, steroid, steroid abuse in international sport, steroid profiles, testosterone

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