Use of stem cells for modeling infant birth defectHemangiomas, which are strawberry like birthmarks commonly seen during early infancy, are usually harmless but can lead to distortion of tissue and vision obstruction in nearly 10 percent cases.

Problematic hemangiomas have been treated with corticosteroids like dexamethasone and prednisone since the 1960s but steroids can fail at times and their action mechanism against hemangioma has remained a mystery.

The study was funded by the National Institutes of Health, the Translational Research Program at Children’s Hospital Boston, a Harvard Skin Diseases Pilot Study Grant, Sheba Medical Center (Israel), and the John Butler Mulliken Foundation.