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  Steroid University Course - 5
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Course 5 – The Negative Effects of Steroid Use

Presented by: www.isteroids.com

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The Negative Effects of Steroid UseAs you are now aware, Anabolic steroids have been proven as being effective in enhancing performance. The trade off, however, is the possibility of negative and side effects, which poses potential danger to the health of the user. Generally, oral steroids have more negative effects than their injectable cousins. Also, steroids containing a 17-alkyl group have potentially more adverse affects, in particular to the liver. Negative side effects are commonly seen when athletes and bodybuilders use more than one harmful compound simultaneously, a practice known as “stacking” or increase dosages which is not uncommon to be seen upwards of 40 times the recommended amount.

The frequency and severity of side effects varies per individual and often has been related directly to several factors such as type of drug, dosage, uration of use and the individual sensitivity and response. Common side effects include:

Inhibition of Natural Hormones

The inhibition of natural hormones is probably the most common side effect experienced with anabolic steroid use. In almost all cases, adding a hormone into your body will trigger its “negative feedback loop,” meaning a message is sent to your endocrine system that it has enough of the hormone and to stop producing it. In other words, when the body recognizes an increase in testosterone it sends a signal to the testes to stop producing it. Therefore, as the level of synthetic hormone rises, the level of natural hormone production falls. In almost all cases, this inhibition is over once the steroids aren’t active in the body anymore. Post Cycle Therapy (PCT)” programs have been developed to combat this. For example, HCG and anti-estrogens are among the drugs used with or after a cycle to avoid inhibition of natural hormone production.

Liver Damage

liver damageSteroids, especially the oral version, like every other ingested chemical are passed through the body’s filtration system: the liver. The liver break down certain enzymes then allows them to be passed through the bloodstream. The constant breakdown of harsh chemicals can eventually become toxic to the liver. Much like alcohol, it is related to dosage and frequency, a few short cycles can be compared to a social drinker, and will not inflict much harm on a healthy liver. When dosages become extreme or the user never comes off the drug it compares to the horror stories of fullblown alcoholism and liver toxicity. When used wisely liver damage can be avoided.

Effects on Cholesterol

Steroids can lower levels of HDL (good cholesterol) while raising LDL (bad cholesterol). Therefore, steroids have been linked to arterial damage. This is only a temporary effect and can be monitored through blood testing while on cycle. Cholesterol levels will most always return to normal post cycle.


Gynecomastia is the medical term for the development of female breast tissue in males. This is due to aromatization, the process in which excess androgens are converted into estrogen. There are warning signals associated with its onset; therefore there is time to discontinue or decrease the dosage of the cycle. Often anti-estrogenic drugs such as Nolvadex or Arimidex or aromitase inhibitors such as Letrozole are used to counteract aromatization and destroy the estrogenic tissue. Advanced or unresponsive Gynecomastia is permanent and can only be removed surgically.


Steroids cause increased production by the skin’s sebaceous glands, which causes the skin to become more oily. When the skin’s oil combines with bacteria, pores can easily become clogged and acne is formed as a result. Steroidal induced acne can be combated with regular cleansing of the skin, products containing salicylic acid and possibly adding topical anti-androgenic products.

Increased Aggression

Increased aggression, commonly dubbed "Roid Rage," by the media is an uncommon side effect. Psychiatric symptoms such as increased violence; mania and psychosis can be associated with AAS. General temperament plays a large role in how a person will respond psychologically to steroids. Those more naturally inclined to be aggressive and temperamental should use steroids with caution.


baldnessIf genetically predisposed to male pattern baldness, steroids can cause a user to start balding more rapidly. The scalp reacts specifically to Dihydrotestosterone (DHT), which many steroids are either derived from or convert to.

In addition to the mentioned side effects several others have been reported including: Cardiovascular problems, virilization effects in females, stunted growth in children, prostate enlargement, high blood pressure, kidney problems, decreased immunity and sterility in both males and females. Although some side effects are permanent, most are often reversible with cessation of the steroid.

Course 6 – Oral Vs. Injectable steroids