Trenbolone
is a 19-nor derived steroid, in the 19-nor
Testosterone
(
Nandrolone)
family. In fact, Trenbolone is structurally similar to
Deca-Durabolin,
differing in the fact that it has a c-9 and c-11 double
bond. The c9 bond serves to prevent any aromatization (conversion) to
estrogen, and thus we see far less water retention with Trenbolone when
we compare it to Deca-Durabolin.
Unlike nandrolone
however The c11 double bond also seems to increase
Androgen Receptor binding quite profoundly (this may also have
something to do with the c9 bond as well). This lack of
estrogenic
activity and powerful ability to bind to the androgen receptor combine
to make Trenbolone a much more powerful androgen than Deca, however. It
also virtually eliminates all water gain and makes the majority of
weight gained on this drug (at least in animal studies) virtually all
new, quality muscle. (1) This has been anecdotally replicated in human
“studies” (read: athletes who use Trenbolone) many times over.
Trenbolone also has the advantage of significantly increasing the level
of the extremely anabolic hormone
IGF-1
within muscle tissue as well as
in the liver. (2) Not only does it increase the levels of IGF-1, by
over 200%, it also causes increased sensitivity to this potent growth
factor (3).
Buy
Trenbolone
Trenbolones binding affinity to the androgen receptor (AR) is
significantly strongly than testosterone (4), and this also contributes
to
anabolism as well as fat loss.
Trenbolone
currently holds the
distinction of being the steroid that binds most tightly to the AR,
currently in circulation today.
Trenbolone promotes
nitrogen retention in muscles (5), thus helping to
build new tissue, as well as being able to interact with the receptors
of the anti-anabolic (muscle growth preventing) glucocorticoid hormones
(6), and thus may also reduce levels of the highly catabolic (muscle
destroying) hormone cortisol.(7) In animal studies, it has
also been
shown to improve feed efficiency and mineral absorption.(8) This serves
to make the food you eat more productive in building new muscle tissue,
and makes it a very effective agent with regards to nutrient
partitioning.(9) Since androgen receptors are found in lipid cells as
well as muscle cells (10), Trenbolone can act directly on the AR in
both of these types of cells to initiate anabolism as well as lipolysis
(fat-burning).(11) In addition, Trenbolone significantly promotes red
blood cell production and also increases the rate of glycogen
replenishment, both of which serve to profoundly improve recovery.(12)
The only draw back to Trenbolone is that it seems to reduce aerobic
capacity in its users, probably owing to bronchial dilation from
increased prostaglandin formation. Also, since it’s a progestin, it can
exacerbate the estrogenic effects of aromatizable
steroids.
Doses are usually in the 75-100mg range, and since the ester length of
this steroid is quite short it needs to be administered via
intramuscular injection every day to every other day, and
Trenbolone is
a favorite on both bulking as well as cutting cycles. It
should be
noted that it is typically used primarily in cutting cycles, since it
is a very potent fat-loss agent.
Trenbolone can be found widely on the Black Market, and implants for
cattle are frequently converted into an injectable or transdermal
compound. Trenbolone, whether it’s made from cattle implants or bought
on the black market pre-made, is typically and significantly more
expensive than other
anabolic
steroids ranging from 15 U.S dollars per
gram of powder up to 150 U.S for a single 10 ml bottle.
References:
1. Br J Nutr. 1978 Nov;40(3):563-72.
2. J Cell Physiol. 2004
Nov;201(2):181-9.
3. Endocrinology. 1989
May;124(5):2110-7.
4. Toxicol Sci. 2002
Dec;70(2):202-11.15
5. J Anim Sci. 1994 Feb;72(2):515-22.
6. APMIS. 2001 Jan;109(1):1-8.
7. J Anim Sci. 1990 Sep;68(9):2682-9.
8. APMIS. 2001 Jan;109(1):1-8.
9. J Anim Sci. 1992
Nov;70(11):3381-90.
10. Am J Physiol. 1998 Jun;274(6 Pt
1):C1645-52.
11. Biochim Biophys Acta. 1995 May
11;1244(1):117-20.
12. J Vet Med A Physiol Pathol Clin
Med. 2001 Aug; 48(6):343-52
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