Femara, also known as Liquifem and Letrozole, is an oral non-steroidal aromatase inhibitor used medically to treat hormonally responsive breast cancer after surgery. Professional sportsmen use Femara for controlling or preventing the formation of excess estrogens, especially after undergoing a steroid cycle involving use of harsh or aromatizable anabolic steroids (especially testosterone derivatives) and performance enhancing drugs.

Femara tablets contain a non-steroidal aromatase inhibitor, letrozole, and inactive tablet ingredients include magnesium stearate, maize starch, microcrystalline cellulose, colloidal silicon dioxide, ferric oxide, hydroxypropyl methylcellulose, lactose monohydrate, polyethylene glycol, sodium starch glycolate, talc, and titanium dioxide. The chemical name of Femara is 4, 4’-(1H-1, 2, 4-Triazol-1ylmethylene) dibenzonitrile and it has the molecular weight of 285.31 g/mol at the base. Letrozole has the molecular formula of C17H11N5.

Letrozole is one of the most trusted drugs for treating specific types of breast cancer (such as hormone-receptor-positive breast cancer) in women after menopause besides proving its usefulness in preventing the cancer from making a return. Since this drug reduces the amount of estrogen the human body makes, it is admired by sportsmen as use of the drug helps them stay away from bloating and estrogenic side effects such as gynecomastia and oily skin. In addition to all these advantages, Letrozole use is also associated with the promotion of spermatogenesis in male patients suffering from non-obstructive azoospermia and treating endometriosis. Femera is also useful in extending help to sportsmen optimize benefits of anabolic steroids, including the promotion of growth hormone, cortisol, SHBG, hepatic production of binding proteins, HDL, and promotion of the growth and development of sexual characteristics.

Letrozole use prevents only ‘harmful estrogen’ and helps the body retain the ‘good estrogen.’ This means that sportsmen using Femara (Letrozole) can still reap benefits of estrogens like healthy immune function, healthy cholesterol levels, joint health, cognitive function, and muscle growth while staying away from bad estrogen side effects (excess estrogen side effects) such as oily skin, acne, and gynecomastia.

The recommended dose of Letrozole (Femara) to treat breast cancer is 2.5 mg once in a day and sportsmen use Liquifem in doses of 0.25-1.0 mg per day, with or without meals. Letrozole abuse can lead to side effects such as loss of appetite, headache, stomach pain, cough, hot flushes, night sweats, vomiting, and breast pain.