Psoriasis treatment possible with lupus drugScientists from the University of Michigan have reported that a compound called benzodiazepine-423 (Bz-423) suppresses growth of cells in a model of psoriasis.

This study available online in the Journal of Pharmacology and Experimental Therapeutics suggested that Bz-423, which is known to minimize harmful side effects of the autoimmune disease lupus, can also be effective in treating psoriasis.

This study was led by Gary Glick, who is the Werner E. Bachmann Collegiate Professor of Chemistry and a professor of biological chemistry in the U-M Medical School. Glick’s coauthors on the paper were James Varani, professor of pathology; Narasimharao Bhagavathula, a research investigator in the pathology department; Hilary Scherzer and Kevin Fay, research associates in pathology; Kent Johnson, professor of pathology; Sewon Kang, professor of dermatology; and Anthony Opipari, assistant professor of obstetrics and gynecology.