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Thursday 29, Apr 2010

  Molecule causing destructive lung inflammation identified

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molecule-causing-destructive-lung-inflammation-identifiedA protein critical to the development of inflammation during lung infection in patients with cystic fibrosis (CF) has been identified by scientists at Children’s Hospital of Pittsburgh of UPMC.

The protein, interleukin-23 (IL-23), is an important finding offering a specific target to the researchers for developing new therapies.

This research by Dr. Kolls and Children’s pulmonologist Patricia Dubin, MD, highlights that IL-23 is an important mediator to an inflammatory response.

Wednesday 03, Feb 2010

  Pneumonia victims can expect relief with steroids

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Pneumonia victims can expect relief with steroidsPatients suffering from pneumonia can expect quick recovery with steroids and antibiotics rather than depending upon antibiotics alone, as per scientists from the UT Southwestern Medical Center.

In a study available online, it was noted that mice infected with a type of severe bacterial pneumonia and treated with a combination of steroids and antibiotics recovered faster besides displaying reduction in the level of lung inflammation than mice treated with antibiotics alone.

The list of other UT Southwestern researchers involved in the study included Dr. Christine Salvatore, infectious-disease fellow in pediatrics; Dr. Chonnamet Techasaensiri, postdoctoral trainee in pediatrics; Dr. Asunción Mejías, assistant professor of pediatrics; Dr. Juan Torres, visiting senior researcher in pediatrics; Kathy Katz, senior research associate in pediatrics; and Dr. Ana Maria Gomez, assistant professor of pathology along with researchers from the University of Milan making contributions.