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Tuesday 29, Jun 2010

  Asthma may effect black teens more than the whites

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Asthma may effect black teens more than the whitesBlack teenagers are more likely to develop steroid-resistant asthma than their white counterparts, according to a research conducted at the National Jewish Medical and Research Center.

It was disclosed in the study that black asthmatic teens are more likely to be sick and suffer from a higher mortality rate than white teens with asthma.

African-American children are prone to steroid-resistant asthma, according to Joseph Spahn, M.D., a pediatric allergist and director of the Immunopharmacology Lab at National Jewish.

The study was published in the Journal of Allergy and Clinical Immunology.

Wednesday 16, Jun 2010

  Oxidative stress research inspires treatment for rare devastating condition

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Oxidative stress research inspires treatment for rare devastating conditionA potential breakthrough was announced by researchers at Queen Mary University London and the University of Leicester for treating Idiopathic pulmonary haemosiderosis, a rare but devastating disease with an unknown cause.

One patient affected with this devastating condition has already been treated by clinicians and scientists from the two universities and noticed promising results.

Preliminary data was published as a letter in the New England Journal of Medicine.

Monday 07, Jun 2010

  Daily calcium supplements can limit early osteoporosis onset

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Daily calcium supplements can limit early osteoporosis onsetChildren afflicted with severe asthma should be taking an over-the-counter calcium supplement and a multi-vitamin every day for preventing loss of bone associated with osteoporosis, as per an article published in the Journal of Allergy and Clinical Immunology.

Joseph Spahn, M.D., an author of the article and a pediatric asthma specialist at National Jewish Medical and Research Center, said that a child does not have to be dependent on steroids to get osteoporosis.

It is worth noting here that inhaled corticosteroids reduce and prevent swelling of the airways and oral (pills or syrup) corticosteroids relax tight muscles around the airways.

Wednesday 26, May 2010

  Protein behind chronic rhinosinusitis with Polyps traced

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Protein behind chronic rhinosinusitis with Polyps identifiedA protein known for stimulating growth of blood vessel was recently found to be behind the cell overgrowth in the development of polyps, which characterize one of the most severe sinusitis forms.

This finding was disclosed by researchers from John Hopkins and is expected to provide a new target to develop novel therapies for treating this disease form that usually resists all presently available treatment options.

Other researchers participating in this study were Hyun Sil Lee, Ph.D., and Allen Myers, Ph.D.

Friday 21, May 2010

  Inhaled and oral steroids influence the risk of cataract

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Inhaled and oral steroids influence the risk of cataractThe use of steroids (corticosteroids) in association with the risk of cataract was recently examined by a study conducted by the Centre for Vision Research, University of Sydney, Australia.

This population-based study, a cohort of the Blue Mountains Eye Study, examined 3,654 Australians, aged 49 years or older, five and 10 years after initial (baseline) examinations were conducted between 1992 and 1994.

It was remarked by lead researcher, Jie Jin Wang, MMed, PhD, Centre for Vision Research that combined use of steroids in cumulatively high doses could raise risks for two types of cataract.

Thursday 20, May 2010

  More asthma symptoms linked with low levels of Vitamin D

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More asthma symptoms linked with low levels of Vitamin DLow vitamin D levels share a relationship with lower lung function and greater medication use in children affected with asthma, as per researchers at National Jewish Health in a paper published online in the Journal of Allergy & Clinical Immunology.

It was reported by Daniel Searing, MD, and his colleagues that vitamin D has the ability to improve the activity of corticosteroids, which are considered to be the most effective of all asthma control medications.

Dr. Leung said that the work suggested that vitamin D improves the anti-inflammatory function of corticosteroids.

Wednesday 12, May 2010

  CH-1504 may prove effective for rheumatoid arthritis

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CH-1504 may prove effective for rheumatoid arthritisA potential oral drug for rheumatoid arthritis (RA), CH-1504, could encourage women in treating their condition earlier since it is less arduous than the presently available treatment forms.

Chelsea Therapeutics, a pharmaceutical company specializing in treatment for RA and other immunological diseases, is presently developing an oral anti-inflammatory medication and conducting Phase I clinical trials in the U.K. to offer a suitable solution for this condition that develops between the ages of 35 and 50 and is 2-3 times more prevalent in women.

CH-1504, the potential therapy, was initially developed by Dr. M. Gopal Nair, a professor and vice-chairman at the department of Biochemistry and Molecular Biology at the University of South Alabama.

Thursday 29, Apr 2010

  Effective treatment for rare devastating condition inspired by oxidative stress research

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effective-treatment-for-rare-devastating-condition-inspired-by-oxidative-stress-researchA potential breakthrough has been announced by researchers at Queen Mary University London and the University of Leicester for treating a rare but devastating medical condition that can affect children and young people.

One patient has already been treated and experienced promising results by the clinicians and scientists from the two universities. The preliminary data was published as a letter in the New England Journal of Medicine.

Jonathan Grigg, Professor of Paediatric Respiratory and Environmental Medicine at Queen Mary University London, said idiopathic pulmonary haemosiderosis is a rare disease with an unknown cause.

Tuesday 23, Mar 2010

  Intersect ENT analyzed

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Intersect ENT analyzedSinexus has changed its name to Intersect ENT and the initial focus of Intersect is a bioabsorbable drug eluting stent for treating patients with sinusitis, which is a debilitating condition that affects around 37 million people each year.

Lisa Earnhardt, President and CEO, said that Intersect is a name that suggests their mission to connect drugs and devices to physicians and patients in need.

The company is aiming to offer less invasive forms of treatment that would result in enhanced outcomes and minimized need for systemic drugs such as oral steroids that can lead to severe side effects.

Saturday 06, Mar 2010

  Protein behind Chronic Rhinosinusitis with Polyps identified

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Protein behind Chronic Rhinosinusitis with Polyps identifiedVascular endothelial growth factor (VEGF), a protein necessary for normal blood vessel growth and stimulating blood vessel growth, has been found to be behind cell overgrowth in the development of polyps characterizing one of the most severe forms of sinusitis.

The finding was revealed by researchers at the Johns Hopkins and appeared in an issue of the American Journal of Respiratory and Critical Care Medicine.

Jean Kim, M.D., Ph.D., assistant professor in the Departments of Otolaryngology and Allergy and Clinical Immunology at the Johns Hopkins University School of Medicine, and a researcher at the Johns Hopkins Allergy and Asthma Center at the Johns Hopkins Bayview Medical Center, said that this kind of sinusitis isn’t subtle.

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