Testosterone deficiency linked to increased mortality in menAccording to as study conducted by the Boston University School of Medicine (BUSM) researchers, deficiencies in androgen hormones, particularly testosterone may be linked increased incidence of cardiovascular disease in men. However, it is alleged to increase the risk of prostate cancer in men.

In the Journal of Andrology, several studies were published linking steroid hormones deficiency to increased mortality in men.

BUSM researchers, in collaboration with researchers from Lahey Clinic Northshore, Peabody, Massachusetts, evaluated several of the published studies linking androgen deficiencies with cardiovascular disease. They have determined that a relationship indeed exist between the two factors.

According to lead author Dr. Abdulmaged M. Traish, professor of biochemistry and urology and director of Laboratories for Sexual Medicine, Institute for Sexual Medicine at BUSM, androgen replacement therapy could be a potential treatment to reduce risk for cardiovascular disease in men. It should be carefully monitored, however, to detect any signs of prostate diseases in men.

Furthermore, the researchers recommend large, long-term, double blind, randomized, placebo controlled clinical trials be performed in order to establish the role of androgen deficiency in increasing the risk of cardiovascular disease in men.

Traish added that these initial findings suggest further studies to be conducted regarding the role of androgens in preventing cardiovascular disease in men.