According to the results of a randomized trial, bacterial corneal ulcers responded no better to adjunctive topical steroids than to placebo.

“A larger study examining only severe corneal ulcers is needed to confirm this supposition,” Nisha R. Acharya, MD, of the University of California San Francisco, and co-authors wrote. “To our knowledge, this is the first large randomized controlled trial to provide evidence regarding the safety and efficacy of the use of corticosteroids in the treatment of bacterial corneal ulcers.”

The study was supported by the National Eye Institute and Alcon/Novartis provided the moxifloxacin used in the study.